James B. Bliska

This study shows that Pseudomonas aeruginosa CF isolate DH1137 reduces inflammasome activation and IL-1β release in alveolar macrophages under hypoxia, potentially aiding immune evasion in cystic fibrosis.

The paper identifies positively selected codon changes in exsA or exsD that hyperactivate the T3SS in P. aeruginosa, leading to hypervirulence through increased T3SS activity and immunopathology.

This paper identifies how Yersinia pestis YopM binds the human pyrin death domain to inhibit inflammasome activation and shows that this interaction is critical for its virulence.

This study examines how Bacteroides colonization affects gut and systemic health in mice, revealing sex-dependent immune responses and macrophage marker changes in specific gut regions.