Francesco Licausi

This study shows that oxygen gradients in developing leaves guide morphogenesis by regulating cell expansion and fate acquisition through the N-degron pathway.

The paper designs a synthetic ERFVII-dependent circuit in yeast to study hypoxia responses, finding similar fast transcriptional responses to plants but highlighting the importance of feedback loops.

The paper shows that KDM7s act as oxygen sensors in Arabidopsis root tips, reprogramming chromatin to enhance hypoxia tolerance by increasing H3K4me3.

The paper analyzes the evolution of oxygen sensing machinery in angiosperms, finding that habitat and anatomy shape diversification of Cys-NDP components while retaining a conserved transcriptional core.

This study identifies TPS5/6/7 as T6P sensors that inhibit SnRK1 activity to coordinate plant growth with sugar availability in Arabidopsis thaliana.

This study shows that reducing activity in Arabidopsis thaliana PCO4 improves flood resilience by stabilizing ERFVIIs, enhancing survival under submergence.

This study replaces Arabidopsis PCOs with NCOs from different species to show how enzyme activity affects hypoxia gene expression and submergence survival, but also impacts growth and biomass.

Hypoxic induction of glycolysis and fermentation genes spans the land plant divisions tested, while oxygen-regulated group VII Ethylene Response Factors (ERFVIIs) carrying Cys2 occur only in vascular plants.

The paper engineers a synthetic system in Arabidopsis thaliana to control hypoxia responses through oxygen-dependent proteolysis, restoring responsiveness in mutants and enabling growth regulation under hypoxic conditions.

The paper shows that H2O2 stabilizes ERFVII transcription factors in reoxygenation, leading to repression of hypoxia markers and activation of oxidative stress genes.

The paper develops a synthetic photoswitch in Arabidopsis thaliana based on cyanobacterial orange carotenoid protein to control light responses in chloroplasts.