Vinay Shukla

Progressive oxygenation of developing leaves directs morphogenesis

This study shows that oxygen gradients in developing leaves guide morphogenesis by regulating cell expansion and fate acquisition through the N-degron pathway.

KDM7-mediated oxygen sensing reprograms chromatin to enhance hypoxia tolerance in the root

The paper shows that KDM7s act as oxygen sensors in Arabidopsis root tips, reprogramming chromatin to enhance hypoxia tolerance by increasing H3K4me3.

Anatomy and habitat shape the oxygen sensing machinery of angiosperms

The paper analyzes the evolution of oxygen sensing machinery in angiosperms, finding that habitat and anatomy shape diversification of Cys-NDP components while retaining a conserved transcriptional core.

TPS Proteins coordinate plant growth with sugar availability via the SnRK1 Kinase

This study identifies TPS5/6/7 as T6P sensors that inhibit SnRK1 activity to coordinate plant growth with sugar availability in Arabidopsis thaliana.

Engineering reduced activity in the oxygen-sensing Arabidopsis thaliana plant cysteine oxidase 4 enzyme results in improved flood resilience

This study shows that reducing activity in Arabidopsis thaliana PCO4 improves flood resilience by stabilizing ERFVIIs, enhancing survival under submergence.

The role of ERFVIIs as oxygen-sensing transducers in the evolution of land plant response to hypoxia

Hypoxic induction of glycolysis and fermentation genes spans the land plant divisions tested, while oxygen-regulated group VII Ethylene Response Factors (ERFVIIs) carrying Cys2 occur only in vascular plants.

Engineering prolyl hydroxylase-dependent proteolysis enables the orthogonal control of hypoxia responses in plants

The paper engineers a synthetic system in Arabidopsis thaliana to control hypoxia responses through oxygen-dependent proteolysis, restoring responsiveness in mutants and enabling growth regulation under hypoxic conditions.

H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress

The paper shows that H2O2 stabilizes ERFVII transcription factors in reoxygenation, leading to repression of hypoxia markers and activation of oxidative stress genes.