Controllable Gap Junctions by Vitamin B12 and Light
Duo Cui, S Liu, Xinyu Huang…·Fei Sun
This paper introduces CarGAP, a chemo-optogenetic tool to reversibly control gap junctions in vertebrates and invertebrates with spatiotemporal precision.
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Hong Kong University of Science and TechnologyORCID 0000-0003-4769-986XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Duo Cui, S Liu, Xinyu Huang…·Fei Sun
This paper introduces CarGAP, a chemo-optogenetic tool to reversibly control gap junctions in vertebrates and invertebrates with spatiotemporal precision.
Yiming Fu, Pham Binh Minh, Sicong He…·Jianan Y. Qu
This study uses high-resolution in vivo imaging to track dynamic retinal changes in glaucoma progression across different phenotypes.
Yang Li, Chuhan Li, Qin Zhou…·Huating Wang
This study uses single-nucleus multiomics to characterize senescence in human skeletal muscle, identifies SASP factors, and proposes Maraviroc as a senotherapeutic for sarcopenia.
Yihui Wang, Zhiyuan Cai, Qian Zeng…·Hao Chen
Genomic Touchstone evaluates genomic language models across 36 tasks and 88 datasets, revealing insights on model performance, scaling, and pretraining strategies.
Yang Li, Chuhan Li, Qiang Sun…·Huating Wang
This study shows that skeletal muscle stem cells modulate their niche in Duchenne muscular dystrophy via the YY1-CCL5 axis, influencing macrophage and fibro-adipogenic progenitor behavior and offering a therapeutic target.
Xue Gang Luo, Danrui Cai, Kejiong Shen…·Yin Shen
This study identifies superior colliculus-projecting GABAergic retinal ganglion cells as mediators of looming-evoked flight response by inhibiting SC neurons via GABA.