Cancer BiologyEMBO Molecular MedicinePeer-reviewed
Targeting de novo cholesterol synthesis in rhabdomyosarcoma induces cell cycle arrest and triggers apoptosis through ER stress-mediated pathways
Nebeyu Yosef Gizaw, Kalle Kolari, Pauliina Kallio…·Riikka Kivelä
This study shows that inhibiting cholesterol biosynthesis in rhabdomyosarcoma cells induces ER stress, apoptosis, and cell cycle arrest, suggesting a new therapeutic strategy for this aggressive cancer.
3 citations