Author

Pauliina Kallio

University of HelsinkiORCID 0000-0001-6374-6203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Antti Sakari RannikkoiD· 1 shared Erika Romppanen· 1 shared Hanna SeppäneniD· 1 shared Kalle KolariiD· 1 shared Kari K. AlitaloiD· 1 shared Lauren J. GerberiD· 1 shared Mariliina ArjamaiD· 1 shared Matilda Roos-MattilaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Antti Sakari RannikkoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 9, 2026

Site-Dependent Decoupling of Drug-Biomarker Associations in Clear Cell Renal Cell Carcinoma Revealed by Functional Profiling of Patient-Derived Cell Models

Michaela Feodoroff, Tamara J. Luck, Romika Kumari…·Vilja M. Pietiäinen

The paper identifies site-dependent drug-biomarker associations in ccRCC using patient-derived models and multi-omic data, revealing discrepancies between genomic predictions and functional drug responses.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyEMBO Molecular MedicinePeer-reviewedNov 17, 2025

Targeting de novo cholesterol synthesis in rhabdomyosarcoma induces cell cycle arrest and triggers apoptosis through ER stress-mediated pathways

Nebeyu Yosef Gizaw, Kalle Kolari, Pauliina Kallio…·Riikka Kivelä

This study shows that inhibiting cholesterol biosynthesis in rhabdomyosarcoma cells induces ER stress, apoptosis, and cell cycle arrest, suggesting a new therapeutic strategy for this aggressive cancer.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky