Author

Prerna Giri

Banaras Hindu UniversityORCID 0000-0003-4775-5067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Bhagyalaxmi MohapatraiD· 2 shared Alexander R. DunniD· 1 shared Alison Schroer Vander RoestiD· 1 shared Amrita MukhopadhyayiD· 1 shared Ashok KumariD· 1 shared Ashok KumariD· 1 shared Daniel BernsteiniD· 1 shared Dharmendra JainiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersGenetics

Bhagyalaxmi MohapatraORCID

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3 papers

Recent·Most cited

Cryo-ET reveals nanoscale thick filamentdisorganization in MYH7 P710R hypertrophiccardiomyopathy cardiomyocytes

Magda Zaoralová, Joseph Yoniles, Prerna Giri, Richard G. Held, Alison Schroer Vander Roest, Peter D. Dahlberg, Daniel Bernstein, Alexander R. Dunn, Leeya Engel

This study uses cryo-ET to show that MYH7 P710R mutations disrupt thick filament organization in HCM cardiomyocytes, leading to sarcomeric disarray and ribosome infiltration.

bioRxiv · Feb 18, 2026 · PreprintCell Biology

Identification and functional characterization of LDB3 gene variants in DCM patients from Indian Population

Bhagyalaxmi Mohapatra, Amrita Mukhopadhyay, Prerna Giri, Dharmendra Jain, Ashok Kumar

This study identifies and functionally characterizes LDB3 gene variants in Indian DCM patients, finding six novel missense variants that affect protein structure, expression, and Z-disc integrity.

bioRxiv · Oct 21, 2025 · PreprintGenetics

Mutations in CSRP3/MLP, a Z-disc associated gene are functionally associated with dilated cardiomyopathy in Indian population

Prerna Giri, Ritu Dixit, Ashok Kumar, Bhagyalaxmi Mohapatra

The paper identifies and functionally characterizes CSRP3 variants in Indian DCM patients, showing reduced protein levels and disrupted interactions, suggesting a role in DCM pathogenesis.

medRxiv · Nov 5, 2021 · PreprintGenetic & Genomic Medicine