Author

Richard G. Held

Howard Hughes Medical InstituteORCID 0000-0001-8231-0341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alexander R. DunniD· 1 shared Alison Schroer Vander RoestiD· 1 shared Axel T. BrüngeriD· 1 shared Chuchu WangiD· 1 shared Daniel BernsteiniD· 1 shared Jiahao LiangiD· 1 shared Joseph YonilesiD· 1 shared Leeya EngeliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alexander R. DunnORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 18, 2026

Cryo-ET reveals nanoscale thick filamentdisorganization in MYH7 P710R hypertrophiccardiomyopathy cardiomyocytes

Magda Zaoralová, Joseph Yoniles, Prerna Giri…·Leeya Engel

This study uses cryo-ET to show that MYH7 P710R mutations disrupt thick filament organization in HCM cardiomyocytes, leading to sarcomeric disarray and ribosome infiltration.

1 citation

humancryo-EM

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NeurosciencebioRxivPreprintOct 19, 2024

In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET

Richard G. Held, Jiahao Liang, Luis R. Esquivies…·Axel T. Brünger

This study uses cryo-electron tomography to visualize the in-situ structure and topography of AMPA receptor scaffolding complexes at molecular resolution.

9 citations

imagingexperimental assay

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