Kian Behbakht

This paper integrates multiple transcriptomics assays to identify cancer biomarkers, finding GBP4 as a predictor of recurrence and immune remodeling.

This study investigates the predictability of progression-free survival in ovarian cancer using NanoString gene expression data from pre- and post-chemotherapy samples, finding low predictability and suggesting the need for larger datasets.

This paper shows that claudin-4 remodels nucleus-cell cycle interactions to maintain genome stability and resist genomic instability-inducing agents in ovarian cancer.

The paper uses spatial data from ovarian cancer tumors to show that spatial organization of the immune microenvironment correlates with patient outcomes and can predict treatment response.

This study identifies Wnt signaling activation as a mechanism of PARP inhibitor resistance in HGSOC and shows that combining PARPi with Wnt inhibitors reduces tumor burden.