Jennifer K. Richer

On the predictability of progression-free survival in ovarian cancer from NanoString gene expression data

This study investigates the predictability of progression-free survival in ovarian cancer using NanoString gene expression data from pre- and post-chemotherapy samples, finding low predictability and suggesting the need for larger datasets.

Androgen receptor interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer.

This study identifies cytoplasmic androgen receptor (AR) localization and novel AR protein interactions in AI-resistant breast cancer, linking them to metabolic shifts and poor prognosis.

Metastasis-associated wound repair promotes reciprocal activation of the lung epithelium and breast cancer metastases during outgrowth

This study shows that lung epithelial cells promote breast cancer metastasis through wound repair mechanisms, and targeting CREB signaling with PDE4 inhibitors can reduce metastatic outgrowth.

An EYA3/NF-κB/CCL2 signaling axis suppresses cytotoxic NK cells in the pre-metastatic niche to promote triple negative breast cancer metastasis

A single N6-methyladenosine site in lncRNA HOTAIR regulates its function in breast cancer cells

This study identifies an m6A modification in HOTAIR lncRNA that regulates its function in breast cancer by affecting chromatin localization and gene expression.