Christina M. Homer

This study uses single-cell RNA-seq and genetic approaches to identify a role for pyropoptosis-like cell death in enteroarthroconidial development in Coccidioides.

This study creates a transcriptomic atlas of Coccidioides development, identifying spherule-enriched transcripts and RYP1-regulated genes critical for virulence.

This study optimizes in vitro spherulation in Coccidioides by adjusting culture conditions, media composition, and arthroconidium preparation to enhance spherule growth and endospore release.

The paper characterizes the phenotypic landscape of Cryptococcus neoformans by analyzing gene deletions and their fitness under various conditions, revealing novel biological insights.

The paper develops a method to infer strain composition in microbial mixed cultures using natural SNPs as barcodes, validated on Coccidioides posadasii isolates and applied to GWAS.

The paper shows that Seb1-mediated RNA polymerase pausing in pericentromeric regions drives heterochromatin formation independently of RNAi.