Author

Jordan E. Burke

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 4 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Organism:yeast· 3 Assay:ChIP-seq· 2 Research Focus:cell-cell communication· 1 Assay:CUT&Tag· 1

Frequent Co-Authors

Hiten D. MadhaniiD· 5 shared John R. YatesiD· 3 shared Adam D LonghurstiD· 2 shared Beiduo RaoiD· 2 shared Jade Sales-LeeiD· 2 shared Jahan‐Yar Parsa· 2 shared James J. MorescoiD· 2 shared Jolene K. DiedrichiD· 2 shared

Activity by Year

2018-2020 · peak 3/yr

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10 top collaborators · 29 mutual co-author links

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5 shared papersMolecular Biology

Hiten D. MadhaniORCID

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5 papers

Recent·Most cited

Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase

Sandra Catania, Phillip A. Dumesic, Harold Pimentel, Ammar Nasif, Caitlin I. Stoddard, Jordan E. Burke, Jolene K. Diedrich, Sophie L. Cooke, Terrance Shea, Elizabeth Gienger, Robert E. Lintner, John R. Yates, Petra Hájková, Geeta J. Narlikar, Christina A. Cuomo, , Hiten D. Madhani

The paper shows that DNA methylation persists in Cryptococcus neoformans despite the loss of a de novo methyltransferase, with methylation patterns maintained through replication and natural selection.

Cell · Jan 1, 2020Peer-reviewedMolecular Biology

A non-Dicer RNase III and four other novel factors required for RNAi-mediated transposon suppression in the human pathogenic yeast C. neoformans

Jordan E. Burke, Adam D Longhurst, Prashanthi Natarajan, Beiduo Rao, S. John Liu, Jade Sales-Lee, Yasaman Mortensen, James J. Moresco, Jolene K. Diedrich, John R. Yates, Hiten D. Madhani

The paper identifies five novel genes required for RNAi-mediated transposon suppression in C. neoformans, revealing a non-Dicer RNase III and nucleolar factors involved in endo-siRNA biogenesis.

G3 Genes Genomes Genetics · May 16, 2019Peer-reviewedMolecular Biology

Chromatin rewiring mediates programmed evolvability via aneuploidy

Cedric A. Brimacombe, Jordan E. Burke, Jahan‐Yar Parsa, Jessica N. Witchley, Laura S. Burrack, Hiten D. Madhani, Suzanne M. Noble

The paper identifies a chromatin-based system in Candida albicans that enables inducible aneuploidy, linking chromatin regulation to antibiotic resistance and evolutionary adaptability.

bioRxiv · Sep 6, 2018 · PreprintGenetics

Polymerase pausing induced by sequence-specific RNA binding protein drives heterochromatin assembly

Jahan‐Yar Parsa, Selim Boudoukha, Jordan E. Burke, Christina M. Homer, Hiten D. Madhani

The paper shows that Seb1-mediated RNA polymerase pausing in pericentromeric regions drives heterochromatin formation independently of RNAi.

Genes & Development · Jul 1, 2018Peer-reviewedMolecular Biology

Spliceosome profiling visualizes the operations of a dynamic RNP in vivo at nucleotide resolution

Jordan E. Burke, Adam D Longhurst, Daria Merkurjev, Jade Sales-Lee, Beiduo Rao, James J. Moresco, John R. Yates, Jingyi Jessica Li, Hiten D. Madhani

The paper develops a method to profile spliceosome-bound RNA at nucleotide resolution in yeast, revealing non-canonical splicing events and substrate features influencing catalytic efficiency.

Cell · May 1, 2018Peer-reviewedMolecular Biology