Alex R. Hopke

This study shows that activating the α7 nicotinic acetylcholine receptor inhibits neutrophil migration and lung recruitment in inflamed mice by suppressing integrin αMβ2 activation.

This study identifies arachidonic acid (AA) as a key regulator of neutrophil swarming, showing that AA release is necessary and sufficient for swarm initiation and scaling.

This study shows that Plasmodium falciparum uses extracellular vesicles to deliver miR-451a to neutrophils, impairing their antimicrobial function and increasing susceptibility to bacterial superinfections.