Author

Lei Ding

Columbia UniversityORCID 0000-0003-4869-8877Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hiroyuki HirakawaiD· 2 shared Baohong ZhaoiD· 1 shared Berthold GöttgensiD· 1 shared Bo SheniD· 1 shared Brian P. Heubel· 1 shared Clifford james RoseniD· 1 shared Edward X. Guo· 1 shared Emmanuelle A. PassegueiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCell Biology

Hiroyuki HirakawaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 29, 2026

Stem cell factor acts locally in the bone marrow to promote stem and progenitor cell maintenance

Maria Angelica Freitas-Cortez, Stefano Comazzetto, Xiang Gao…·Sean J. Morrison

This study shows that SCF produced locally in bone marrow stromal and endothelial cells supports hematopoietic stem and progenitor cell maintenance, while systemic SCF does not.

DOI 10.64898/2026.09.28.755094

mouseexperimental assay

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Cell BiologyBloodPeer-reviewedOct 8, 2025

Inflammation perturbs hematopoiesis by remodeling specific compartments of the bone marrow niche

James W. Swann, Ruiyuan Zhang, Evgenia V. Verovskaya…·Emmanuelle A. Passegue

The paper identifies two bone marrow compartments and shows inflammation affects them differently, with type I interferon causing changes in mesenchymal stromal cells.

8 citationstop 3%

mousescRNA-seq

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Molecular BiologyeLifePeer-reviewedJun 21, 2021

Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells

Nicole Aaron, Michael James Kraakman, Qiuzhong Zhou…·Li Qiang

This study shows Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells toward adipogenesis through C3 and Wnt/β-catenin signaling inhibition.

70 citationstop 3%

mousehuman

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