Author

Thomas Crowhurst

Lyell McEwin HospitalORCID 0000-0003-4873-5439Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Eugene RoscioliiD· 2 shared Anton BlencoweiD· 1 shared Arash BadieiiD· 1 shared Benjamin T. KoppiD· 1 shared Duc Q Doan· 1 shared Emily LawtoniD· 1 shared Hubertus P. A. JersmanniD· 1 shared James M Cooper· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Eugene RoscioliORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 2, 2026

Azithromycin Derivatives to Mitigate Off-Target Inhibition of Autophagy and Retain Beneficial Host Directed Effects

Duc Q Doan, Shawn WH Liu, Samuel Clark…·Eugene Roscioli

This study develops AZM derivatives that maintain anti-inflammatory effects while allowing autophagy, reducing resistance risk.

DOI 10.64898/2026.09.01.748460

humanproteomics

𝕏 PostBluesky

Molecular BiologyInternational Journal of Molecular SciencesPeer-reviewedJun 13, 2026

Autophagy is suppressed in peripheral blood mononuclear cells during chronic obstructive pulmonary disease.

James M Cooper, Shiye Chen, Susan Elizabeth Lester…·Eugene Roscioli

The paper shows that autophagy is suppressed in peripheral blood mononuclear cells of COPD patients, as indicated by reduced autophagic flux and fewer autophagy-related vacuoles.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky