Matthew Paul Gillum

This study identifies FGF21 as a specific ethanol-induced hormone through proteomic profiling of acute alcohol intoxication in humans.

This paper identifies SLC25A34 as a key regulator of interorganellar lipid cycling, integrating circadian rhythms, diet, and temperature to control thermogenic metabolism.

The paper identifies a loss-of-function variant in GFRAL associated with increased alcohol consumption in humans and shows GDF15 reduces alcohol drinking in mice.

This study shows that FGF21 deletion worsens hepatic dysfunction in rats fed a MASH diet and alcohol, but does not affect body weight or liver transcriptome in the diet model.