Jee Hyun Park

The paper integrates mouse and human microglia transcriptomics to identify AD-related pathways and drugs using TransComp-R, finding FDA-approved drugs that mimic healthy human microglia in mice.

The paper develops a cross-species translation framework to identify therapeutic targets for late-onset Alzheimer's disease using mouse models and human data.

The paper identifies conserved molecular pathways in spaceflight-induced sarcopenia using cross-species analysis and develops a model linking transcriptional changes to locomotion deficits.

This paper uses cross-disease modeling to identify T2D biomarkers predictive of Alzheimer's disease and suggests a T2D medication that may prevent AD onset.

This study identifies endothelial RhoA activation as a key driver of tumor cell transendothelial migration and metastasis, showing it can be inhibited to reduce metastatic potential.