Author

Constantinos Marios Mikelis

Texas Tech University Health Sciences CenterORCID 0000-0002-6119-3307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Racheal Grace Akwii· 2 shared Boksik ChaiD· 1 shared Chonghe ZhangiD· 1 shared Colleen L. DoçiiD· 1 shared Dean Y. MaedaiD· 1 shared Dongwon Choi· 1 shared Fatema Tuz ZahraiD· 1 shared Hirotake IchiseiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Racheal Grace Akwii

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintSep 22, 2024

Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis

Md Sanaullah Sajib, Fatema Tuz Zahra, Μαργαρίτα Λάμπρου…·Constantinos Marios Mikelis

This study identifies endothelial RhoA activation as a key driver of tumor cell transendothelial migration and metastasis, showing it can be inhibited to reduce metastatic potential.

2 citations

humanmouse

Developmental BiologyJCI InsightPeer-reviewedJun 16, 2020

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling

Xin Geng, Keisuke Yanagida, Racheal Grace Akwii…·R. Sathish Srinivasan

This study identifies S1PR1 as a regulator of lymphatic vessel quiescence by inhibiting LSS-dependent VEGF-C signaling in lymphatic endothelial cells.

62 citationstop 4%

mouseexperimental assay