ImmunologyNature CommunicationsPeer-reviewed
NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates
Damien Glon, Quentin Riller, Lucı́a Álvarez…·Yves Gaudin
This study shows NAP1 switches from enhancing to limiting TBK1 activity through condensate formation, affecting IFN induction and linking to interferonopathies.
DOI 10.1038/s41467-026-76769-w