BioengineeringbioRxivPreprint
Structure-Function Analysis of the FCRL5-IgG1 Fc Complex Reveals an Unappreciated Effect of Fc-Silent Antibodies on B cells
Bart M. Herpers, Mo Guo, Sanghwan Ko…·George Georgiou
This study shows Fc-silencing mutations in therapeutic antibodies do not block FCRL5 binding, potentially affecting B cell function through novel Fc-FCRL5 interactions.
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