Mo Guo

This study visualizes G2L4 reverse transcriptase's role in DNA repair via microhomology-mediated end joining using high-speed atomic force microscopy.

This paper determines the structure of mouse FcγRIV and uses it to engineer a human Fc variant that enhances cross-species FcγR recognition.

This study shows Fc-silencing mutations in therapeutic antibodies do not block FCRL5 binding, potentially affecting B cell function through novel Fc-FCRL5 interactions.

This study determines the structural basis for how a domesticated reverse transcriptase evolved to function in DNA repair by revealing key structural adaptations in its apoenzyme and DNA synthesis complexes.