Daniel W. Grupe

IBMMA improves neuroimaging analysis by handling missing data and large datasets, revealing new brain region findings overlooked by traditional methods.

The paper examines thalamic volume differences in trauma-exposed individuals with PTSD, MDD, and controls, finding specific volume reductions and associations with symptom severity and childhood trauma.

The paper introduces the multimedia R package for mediation analysis of microbiome data, demonstrating its ability to uncover mechanistic interactions in two case studies.

This paper classifies PTSD vs. controls using MRI data from multiple sites, finding better performance when distinguishing PTSD from trauma-unexposed controls than trauma-exposed controls, and showing DVAE improves generalizability.

This study finds smaller total and subregional cerebellar volumes in PTSD compared to controls using a large dataset and advanced parcellation methods.

This paper compares four methods for harmonizing cortical thickness data across multiple sites and finds that ComBat-GAM is most effective in detecting case-control differences and age-related cortical thinning.

This study finds that long-term meditation enhances attention and strengthens posterior cingulate-rostrolateral prefrontal cortex connectivity in meditators compared to controls.

The paper examines the relationship between perceived threat bias, PTSD symptoms, and hippocampal volume in combat veterans, finding an inverse correlation between perceived threat bias and hippocampal volume.

This study identifies hippocampal subfield volume differences in PTSD and depression across 31 cohorts, finding depression has a stronger effect than PTSD, especially in CA1, with comorbid cases showing more pronounced changes.

This study identifies reduced fractional anisotropy in the tapetum region of the corpus callosum in PTSD patients using a large multi-cohort analysis of diffusion MRI data.

The paper investigates the relationship between PTSD symptoms, pulse rate variability, and ventromedial prefrontal cortex activation in combat-exposed veterans, finding associations between reduced HF-PRV and impaired vmPFC function.

The paper investigates how emotional processing of stimuli affects subsequent neutral social stimuli processing, finding individual differences in affective biasing and memory.