Author

Hiva Doustmohammadi

Universitat de GironaORCID 0000-0003-4941-7782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Cindy KlausiD· 1 shared James S. FraseriD· 1 shared Janet H. SancheziD· 1 shared Niayesh ZarifiiD· 1 shared Pooja AsthanaiD· 1 shared Roberto A. ChicaiD· 1 shared Rojo V. RakotoharisoaiD· 1 shared Serena E. HuntiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Cindy KlausORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedSep 30, 2025

Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release

Niayesh Zarifi, Pooja Asthana, Hiva Doustmohammadi…·Roberto A. Chica

This study shows that distal mutations improve enzyme catalysis by enhancing substrate binding and product release, working with active-site mutations to increase overall activity.

36 citationstop 1%

experimental assay

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