Přemysl Jiruška

This study uses longitudinal imaging in a mouse model of FCD II to show lesion expansion, hypoactive dysmorphic neurons, and loss of pre-discharge neuronal recruitment over time.

This study examines how partial lesions of hypocretin neurons in rats affect sleep regulation under increased sleep pressure, finding accelerated slow wave sleep and reduced theta frequency.

The paper tracks how high-frequency oscillations evolve in a mouse model of focal cortical dysplasia type II, showing contralateral cortex recruitment into the epileptic network over time.

The paper tracks neuronal loss in an FCD mouse model and finds no reduction in seizures or neuron elimination with DQ treatment, suggesting strain-specific effects.

This study uses computational modeling and in vitro experiments to investigate how low-frequency electrical stimulation delays seizures by modulating ion dynamics and neuronal excitability in rat hippocampal slices.

This study investigates seizure occurrence in FCD type II by analyzing lesion position and cytoarchitectural changes in a mouse model.

This study identifies critical slowing as a biomarker for seizure susceptibility using long-term iEEG recordings from epilepsy patients.

This study investigates how synaptic and non-synaptic mechanisms interact during seizure activity in rat hippocampal slices, finding that non-synaptic processes drive seizure onset while synaptic inhibition modulates event progression.