Vicky Bousgouni

This study assesses the reproducibility of a 3D spheroid-based assay across four institutes using dual-view oblique plane microscopy and finds high consistency in treatment effects with low technical noise.

The paper identifies actin nucleators as essential for protecting replication forks by modulating RPA activity and preventing ssDNA degradation during replicative stress.

This study investigates neurodegeneration in Xeroderma pigmentosum using stem cell-derived neurons, identifying endoplasmic reticulum stress and UPS dysfunction as key factors and developing an early detection assay.

The paper uses geometric deep learning to analyze 3D cell shapes from melanoma cells, identifying morphological signatures and predicting small molecule mechanisms.

The paper identifies Brca1, Bard1, and Wdr5 as factors linking DNA damage response to MET during reprogramming, using siRNA screening and colony morphology analysis.