Armen Saghatelyan

This study shows that purinergic receptor activation can correct endothelial dysfunction linked to autism in a mouse model by restoring bioenergetic function and cerebrovascular reactivity.

The paper shows that ependymal cell cilia beating regulates neural stem cell quiescence through mechanical forces involving PKD1/2 and TRPM3.

This paper introduces UTMM, a method to simultaneously measure transcriptomes and mechanical properties in intact embryos, revealing coupling between RNA expression and intracellular compliance during early development.

The paper shows that different odor learning paradigms induce distinct structural plasticity in adult-born interneuron spines in the olfactory bulb.

This study shows SARS-CoV-2 spike protein induces immunoreactivity in brain pericytes without viral infection, contributing to microvasculature injury in COVID-19.

This study shows that autophagy is essential for midbrain dopaminergic axon development and responsiveness to guidance cues, with knockout of autophagy genes causing axonal swellings and impaired branching.

The paper shows that ATP/ADP levels and autophagy interact to regulate neuronal migration by controlling cell pausing and focal adhesion recycling in mice.