Martin Lévesque

This study investigates the role of VGluT3 in DRN 5-HT neurons by manipulating its expression and assesses effects on synaptic structure and behavior.

The paper identifies axon-specific mRNA translation in dopaminergic neurons and shows how it regulates axon development and connectivity.

This study identifies sex-specific transcriptional changes in mPFC-NAc pathway neurons under chronic stress, revealing Xlr4b as a stress susceptibility driver in males.

This study shows that increasing SLP-2 levels reduces alpha-synuclein-induced mitochondrial damage and neurodegeneration in Parkinson's disease models.

The paper investigates dopamine signaling in mice during reward and aversive tasks, finding distinct spatial patterns and encoding mechanisms for reward and aversive signals.

This study investigates how chronic social defeat stress affects dopaminergic pathways in male and female mice, revealing sex-specific molecular changes in the VTA, NAc, and mPFC.

This study shows that RIT2 inhibits LRRK2 kinase activity, reduces aSyn inclusions, and protects neurons in Parkinson's disease models.

This study shows that autophagy is essential for midbrain dopaminergic axon development and responsiveness to guidance cues, with knockout of autophagy genes causing axonal swellings and impaired branching.