Baptiste Lacoste

This study shows that purinergic receptor activation can correct endothelial dysfunction linked to autism in a mouse model by restoring bioenergetic function and cerebrovascular reactivity.

The paper identifies neuronal lipid droplets as conserved structures that regulate energy homeostasis with sex-biased effects in flies and mice.

This study examines metabolic, epigenetic, and transcriptomic changes in astrocytes from a mouse model of 16p11.2 deletion ASD syndrome, revealing sex-specific molecular alterations.

This study examines glial-vascular interactions in zebrafish brains across development, showing increasing glial coverage over time, with lower adult coverage compared to mammals.

The paper explains how electron tomography (ET) can be used to study the ultrastructure of brain endothelial cells in three dimensions.

This study identifies Hmgb1 in astrocytes as critical for postnatal astrocyte morphogenesis and cerebrovascular maturation, affecting endothelial ultrastructure and neurovascular coupling in adult mice.

The paper identifies two distinct astroglial phenotypes across mouse cortical development and reveals significant sex differences in developmental gene expression patterns.