Author

Hussam Z. Alshareef

University of Nevada, RenoORCID 0000-0003-4980-3456Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander M. van der LindeniD· 2 shared Emmanuel AdeyemiiD· 1 shared Everett Rojas· 1 shared Jaffar M. BhatiD· 1 shared Pedro MiuraiD· 1 shared Thomas Ballinger· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersGenomics

Alexander M. van der LindenORCID

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2 papers

Recent·Most cited

GenomicsG3 Genes Genomes GeneticsPeer-reviewedJan 22, 2026

The RNA-binding protein NOVA-1 regulates circRNA expression, alternative splicing, and aging in C. elegans

Emmanuel Adeyemi, Hussam Z. Alshareef, Jaffar M. Bhat…·Alexander M. van der Linden

This study shows that NOVA-1 regulates circRNA expression, alternative splicing, and aging in C. elegans by modulating splicing events and circRNA production.

2 citations

C. elegansbulk RNA-seq

𝕏 PostBluesky

NeuroscienceFrontiers in Aging NeurosciencePeer-reviewedMar 24, 2025

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimers disease

Hussam Z. Alshareef, Thomas Ballinger, Everett Rojas, Alexander M. van der Linden

The paper shows that loss of age-accumulated circ-crh-1 circRNAs reduces Aβ-induced toxicity in C. elegans, suggesting a protective role against Alzheimer's disease.

6 citations

C. elegansexperimental assay

𝕏 PostBluesky