Author

Catherine A. Burkhart

Buffalo BioLabsORCID 0009-0000-1906-6809Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:experimental assay· 1

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Alfiya F. SafinaiD· 1 shared Andrei V. GudkoviD· 1 shared Britney Lipchick· 1 shared Costakis G. FrangouiD· 1 shared Elimelech NesheriD· 1 shared Igor E. KomaniD· 1 shared Jianmin WangiD· 1 shared Katerina I. LeonovaiD· 1 shared

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Alfiya F. SafinaORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintJun 28, 2017

Transcription of Repeats Activates INterferon (TRAIN) in response to chromatin destabilization induced with anti-cancer small molecule

Katerina I. Leonova, Alfiya F. Safina, Elimelech Nesher…·Katerina V. Gurova

The paper shows that chromatin destabilizing drugs like curaxin induce an interferon response (TRAIN) through repeat transcription, independent of p53 status, and may prevent cancer by eliminating epigenetically unstable cells.

DOI 10.1101/142471

experimental assay

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