Author

Sarah Domoney

University College LondonORCID 0009-0000-2655-0260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Christy HungiD· 1 shared David KlenermaniD· 1 shared Emre FertaniD· 1 shared Frederick J. LiveseyiD· 1 shared Patricia L. Dyal· 1 shared Rickie PataniiD· 1 shared Sian GoldsworthyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Christy HungORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMay 27, 2025

Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes

Sian Goldsworthy, Emre Fertan, Patricia L. Dyal…·Christy Hung

This study shows human astrocytes generate and release amyloid-β aggregates under lysosomal stress, contributing to extracellular Aβ accumulation in Alzheimer's disease.

DOI 10.1101/2025.05.27.656416

humanbulk RNA-seq

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