Author

Christy Hung

The Francis Crick InstituteORCID 0000-0003-0056-7587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Frederick J. LiveseyiD· 2 shared Alastair D. ReithiD· 1 shared Alessio StranoiD· 1 shared Andrew R. Bassett· 1 shared Ashley Campbell· 1 shared Benjamin FalconiD· 1 shared Bernardino Francesco GhettiiD· 1 shared David KlenermaniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Frederick J. LiveseyORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 27, 2025

Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes

Sian Goldsworthy, Emre Fertan, Patricia L. Dyal…·Christy Hung

This study shows human astrocytes generate and release amyloid-β aggregates under lysosomal stress, contributing to extracellular Aβ accumulation in Alzheimer's disease.

DOI 10.1101/2025.05.27.656416

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 11, 2020

Whole genome CRISPR screens identify a LRRK2-regulated pathway for extracellular tau uptake by human neurons

Lewis Evans, Alessio Strano, Eleanor J. Tuck…·Frederick J. Livesey

The paper identifies LRRK2-regulated pathways for extracellular tau uptake in human neurons using CRISPR screens, showing LRRK2's role in monomeric tau endocytosis.

19 citations

humanCRISPR screen

𝕏 PostBluesky