Author

Johan David Polet

University of GroningenORCID 0009-0000-2751-5635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Maurice DekkeriD· 1 shared Patrick R. OnckiD· 1 shared Vasista AdupaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Maurice DekkerORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 27, 2026

A two-bead-per-aminoacid coarse-grained MD model with hydrogen bonding (2BPA-HB) to probe DNAJB6b-mediated suppression of polyglutamine aggregation in Huntingtons disease

Vasista Adupa, Johan David Polet, Maurice Dekker, Patrick R. Onck

This paper develops a coarse-grained MD model to study DNAJB6b's role in suppressing polyglutamine aggregation in Huntington's disease, finding that DNAJB6b co-condensates with polyQ and inhibits amyloid formation.

1 citation

protein structuremechanistic / dynamical model

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