Author

Phyo Wei Win

Western UniversityORCID 0009-0000-2761-0800Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Charles NewcombiD· 2 shared Christina A. CastellaniiD· 2 shared Dan E. ArkingiD· 2 shared Elly H. ShiniD· 1 shared Jiaqi XieiD· 1 shared Julia NguyeniD· 1 shared Shaopeng Zeng· 1 shared Tyler Shin Nagano· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersGenetics

Charles NewcombORCID

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2 papers

Recent·Most cited

GeneticsExperimental Cell ResearchPeer-reviewedFeb 25, 2026

Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics

Jiaqi Xie, Phyo Wei Win, Charles Newcomb…·Dan E. Arking

The paper investigates transcriptomic and methylomic changes in HEK 293T cells with reduced mtDNA copy number, revealing compensatory mechanisms in mitochondrial replication and metabolic pathways.

1 citation

humanbulk RNA-seq

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GenomicsbioRxivPreprintJan 29, 2024

Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome

Julia Nguyen, Phyo Wei Win, Tyler Shin Nagano…·Christina A. Castellani

This study shows that reducing mitochondrial DNA copy number in human cells changes nuclear DNA methylation and gene expression, revealing pathways linked to disease.

2 citations

humanDNA methylation

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