Darshika Bohra

The paper shows that enhancer activation during estrogen signaling indirectly represses neighboring non-target genes within the same TAD through dynamic chromatin interactions.

This study shows HP1 and HP1β promote differential recruitment of HR and NHEJ factors at DSBs, with HP1 phase separation essential for HR recruitment.

The paper develops a microscopy acquisition stack and applies it to study DNA damage response without operator intervention.