Author

Zubairul Islam

Tata Institute of Fundamental Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Dimple NotaniiD· 3 shared Anurag Kumar SinghiD· 2 shared Bharath SaravananiD· 2 shared Kaivalya WalavalkariD· 2 shared Umer FarooqiD· 2 shared Aprotim MazumderiD· 1 shared Awadhesh PanditiD· 1 shared Darshika BohraiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

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3 papers

Recent·Most cited

Ligand-dependent Enhancer Activation Indirectly Modulates Non-target Promoters in a Chromatin Domain

Darshika Bohra, Zubairul Islam, Sundarraj Nidharshan, Aprotim Mazumder, Dimple Notani

The paper shows that enhancer activation during estrogen signaling indirectly represses neighboring non-target genes within the same TAD through dynamic chromatin interactions.

eLife · Jul 7, 2026Peer-reviewedMolecular Biology

Active enhancers strengthen insulation by RNA-mediated CTCF binding at TAD boundaries

Zubairul Islam, Bharath Saravanan, Kaivalya Walavalkar, Umer Farooq, Anurag Kumar Singh, Radhakrishnan Sabarinathan, Jitendra Thakur, Awadhesh Pandit, Steven Henikoff, Dimple Notani

The paper shows boundary-associated RNAs enhance TAD insulation by promoting CTCF clustering at TAD boundaries.

Genome Research · Jan 1, 2023Peer-reviewedGenomics

Ligand dependent gene regulation by transient ERα clustered enhancers

Bharath Saravanan, Deepanshu Soota, Zubairul Islam, Ranveer Singh Jayani, Rajat Mann, Umer Farooq, Sweety Meel, Kaivalya Walavalkar, Srimonta Gayen, Anurag Kumar Singh, Sridhar S. Hannenhalli, Dimple Notani

The paper shows that unliganded ERα pre-marks enhancer sites, which form 3D clusters upon ligand exposure, driving transient gene expression.

PLoS Genetics · Jan 6, 2020Peer-reviewedMolecular Biology