Author

Esme Hutton

University of YorkORCID 0009-0000-4237-6071Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Martin A. FascioneiD· 2 shared Nathalie Yvonne Micheline SignoretiD· 2 shared Adam DowleiD· 1 shared Adam DuxfieldiD· 1 shared Adriana BuskiniD· 1 shared Amanda R. NobleiD· 1 shared Anastasia C. HepburniD· 1 shared Ann HedleyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Martin A. FascioneORCID

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2 papers

Recent·Most cited

Characterisation of prostate cancer sialome re-engineering via CMAH transfection reveals a bystander effect that propagates Neu5Gc presentation to neighbouring cells

Yumiko Uno, Amanda R. Noble, Esme Hutton, Nathalie Yvonne Micheline Signoret, Martin A. Fascione

This study shows that expressing rat CMAH in prostate cancer cells leads to Neu5Gc presentation on cell-surface glycans, which can be transferred to neighboring cells, suggesting a bystander effect in the tumor microenvironment.

bioRxiv · Sep 11, 2026 · PreprintCancer Biology

The Androgen Receptor and MYC synergise to modulate the synthesis of Siglec-7 ligands in prostate cancer

Adam Duxfield, Rebecca Garnham, Esme Hutton, Adam Dowle, Jamie Wills, Sara Luzzi, Ryan Nelson, Emma Lishman-Walker, Rianna Magee, Adriana Buskin, Anastasia C. Hepburn, Emirhan Tekoglu, Kaidan Maloney-Friar, Fiona M. Frame, Norman J. Maitland, , Emma Scott

This study shows that the androgen receptor and MYC work together to control the production of Siglec-7 ligands in prostate cancer by regulating sialylation and glycopeptide profiles.

bioRxiv · Oct 15, 2025 · PreprintCancer Biology