Cancer BiologybioRxivPreprint
CA19-9 induces microenvironment remodeling in pancreatic ductal adenocarcinoma
Jasper Hsu, Hyemin Song, Satoshi Ogawa…·Dannielle D. Engle
This study identifies CA19-9's role in remodeling the PDAC tumor microenvironment by inducing IL1a and TGFb, leading to immunosuppressive changes that can be mitigated by blocking these factors.
DOI 10.64898/2026.05.22.727290