Developmental BiologyScience AdvancesPeer-reviewed
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Maternal-fetal immune conflict contributes to male-specific impairments in a mouse model of neurodevelopmental disorders
Irene Sanchez-Martin, Bharti Kukreja, Paige Henderson…·Lucas Cheadle
A poly(I:C) dose at E12.5 causes placental junctional-zone breakdown, amniotic inflammation and developmental defects in a male-only subset of embryos within 24 hours, dependent on maternal IL-6.