NeuroscienceMolecular AutismPeer-reviewed
Loss of the MeCP2 gene in parvalbumin interneurons leads to an inhibitory deficit in the amygdala and affects its functional connectivity.
Maj Liiwand, Joni Haikonen, Bojana Kokinovic…·Maria Ryazantseva
This study shows that losing the MeCP2 gene in parvalbumin interneurons reduces inhibitory signaling in the amygdala and disrupts functional connectivity with the hippocampus and prefrontal cortex.
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