Sari E. Lauri

This study shows that early life stress increases neuronal avalanche spread in the prefrontal-amygdala network in male rats but not females, indicating sex-dependent effects on brain network dynamics.

The paper examines developmental changes in neuronal avalanches in the mPFC-BLA circuit of rats, finding distinct critical dynamics in each region.

This study shows that losing the MeCP2 gene in parvalbumin interneurons reduces inhibitory signaling in the amygdala and disrupts functional connectivity with the hippocampus and prefrontal cortex.

This study investigates how early-life stress affects glutamatergic inputs to interneurons in the mouse amygdala, revealing sex-specific changes in circuit dynamics and fear processing.

This study shows that GluK1 kainate receptors are essential for the development and maintenance of parvalbumin interneurons in the amygdala, affecting their function and behavior.

This study shows that arginine vasopressin excites neonatal serotonergic neurons in the dorsal raphe nucleus both in vitro and in vivo, contrasting its inhibitory effects on cortical networks.

This study shows that GluK1 kainate receptors in PV interneurons regulate amygdala excitability and behavioral response to chronic stress through GABAB receptor-mediated inhibition.

This study shows that TrkB activation in PV+ interneurons is essential for antidepressant-induced behavioral flexibility and synaptic plasticity in spatial and fear memory.

This study investigates how early life stress affects prefrontal-amygdala connectivity in rats, finding transient increases in GABAergic inhibition and reduced network synchronization in males but not females.

This study identifies a direct binding of antidepressants to TRKB receptors, revealing a mechanism linking molecular interactions to antidepressant effects.

The paper uses optogenetics to activate TrkB receptors in the ventral hippocampus, enhancing plasticity and improving fear extinction in mice.

The paper shows that optogenetic activation of TrkB receptors in PV interneurons increases cortical plasticity by altering neuronal excitability and gene expression.

The paper shows that kainate-type glutamate receptors regulate the development of intrinsic glutamatergic connections in the amygdala during early postnatal life.

This study shows that isoflurane anesthesia produces antidepressant-like effects in rodents by activating TrkB signaling and related molecular pathways.