Author

Lewis E. Kay

University of TorontoORCID 0009-0000-6823-4776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aidan EstelleiD· 1 shared Bernd BukauiD· 1 shared Jeffrey P. BoniniD· 1 shared Julie Deborah Forman-KayiD· 1 shared Lucia SvobodaiD· 1 shared Massimiliano BonomiiD· 1 shared Nicolas Bolik-CouloniD· 1 shared Rashik AhmediD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Aidan EstelleORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 27, 2026

NMR-measured Per-residue Electrostatic Potentials Reveal the Importance of Arginine-Lysine Balance on the Conformational Ensemble of Disordered Histone H3 Tails in Nucleosome Core Particles

Aidan Estelle, Vincent Schnapka, Nicolas Bolik-Coulon…·Lewis E. Kay

The paper measures electrostatic potentials of histone H3 tails using NMR and simulations to show how arginine-lysine balance affects their conformational behavior in nucleosome core particles.

DOI 10.64898/2026.10.25.761679

protein structureexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintOct 22, 2026

Phase separation reshapes the conformational energy landscape of a chaperone to prime its activity

Rashik Ahmed, Lucia Svoboda, Rhea P Hudson…·Lewis E. Kay

This study shows how phase separation alters the conformational dynamics of DNAJB1, priming it for HSP70 binding and stress granule disassembly.

DOI 10.64898/2026.10.17.759813

protein structureexperimental assay

𝕏 PostBluesky