Molecular BiologybioRxivPreprint
Unexpected ribosome turnover during prolonged translation inhibition
Paul J. Russell, Caleb A. Clark, Mia Ashriem, Michael G. Kearse
This study shows that prolonged translation inhibition by cycloheximide causes proteasome-dependent degradation of ribosomal RNA and proteins, revealing a new quality control pathway called GRIP.
DOI 10.64898/2026.05.06.723260