Author

Brandon M. Waddell

University of SaskatchewanORCID 0009-0000-7906-7782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:C. elegans· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Cheng‐Wei WuiD· 2 shared Abd-Al-Wahab Khawaja· 1 shared Alexandra HarknessiD· 1 shared Carlos Zapien Verdugo· 1 shared Cheng-Wei Wu· 1 shared Hadi TabarraeiiD· 1 shared Hannah M. BrooksiD· 1 shared Keith Patrick ChoeiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetics

Cheng‐Wei WuORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 6, 2026

Discovery of a small peptide that activates both APCCdc20 and APCCdh1 in yeast, driving increased lifespan

Rachel Elizabeth Harris, Spike D. L. Postnikoff, Nishita K Shukla…·Troy A. A. Harkness

The paper identifies a small peptide, C43-4, that activates the APC Cdh1 complex in yeast, increasing chronological lifespan and showing evolutionary conservation in C. elegans.

DOI 10.64898/2026.02.17.706436

yeastexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 12, 2023

A role for the C. elegans Argonaute protein CSR-1b isoform in small nuclear RNA 3' processing

Brandon M. Waddell, Cheng‐Wei Wu

The paper identifies csr-1b as a novel regulator of the Integrator complex involved in snRNA 3' processing through RNAi screens and isoform analysis.

DOI 10.1101/2023.10.12.562094

C. elegansbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintJun 13, 2022

CCR4-NOT subunit CCF-1/CNOT7 interacts with the PAL-1/CDX-1 transcription factor to regulate multiple stress responses in Caenorhabditis elegans

Hadi Tabarraei, Brandon M. Waddell, Kelly Raymond…·Cheng-Wei Wu

The paper identifies CCF-1/CNOT7 as a CCR4-NOT subunit required for C. elegans stress response, interacting with PAL-1 to regulate elt-2 and elt-3 expression.

DOI 10.1101/2022.06.13.495535

C. elegansbulk RNA-seq

𝕏 PostBluesky