Author

Harry J Ashbaugh

Van Andel InstituteORCID 0009-0000-8015-8331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Derek H. JanssensiD· 2 shared Emma BairdiD· 2 shared Alexandria P. EikeniD· 1 shared Lola PiperiD· 1 shared Olivia A. PentecostiD· 1 shared Sara M. NowinskiiD· 1 shared Wenjie Sun· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersGenomics

Derek H. JanssensORCID

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2 papers

Recent·Most cited

Engineered Tn5 Variants Enhance CUT&Tag Fidelity for Transcription Factors

Lola Piper, Emma Baird, Harry J Ashbaugh, Olivia A. Pentecost, Sara M. Nowinski, Derek H. Janssens

This paper improves CUT&Tag for transcription factors by engineering Tn5 variants, enhancing recovery of TF binding sites in mouse cells and revealing distinct chromatin interaction modes.

bioRxiv · Oct 28, 2026 · PreprintGenomics

CoCUT&Tag maps linked chromatin states at single-molecule, single-cell resolution

Wenjie Sun, Emma Baird, Harry J Ashbaugh, Alexandria P. Eiken, Derek H. Janssens

The paper introduces CoCUT&Tag, a method to measure co-occupancy of two chromatin features at single-cell resolution, and shows that bivalent chromatin enhances gene activation during hematopoietic differentiation.

bioRxiv · Apr 29, 2026 · PreprintGenomics