Alexandria P. Eiken

The paper introduces CoCUT&Tag, a method to measure co-occupancy of two chromatin features at single-cell resolution, and shows that bivalent chromatin enhances gene activation during hematopoietic differentiation.

This paper evaluates SpiD3, a novel spirocyclic dimer, showing potent anti-leukemic effects in CLL cells, including resistance to ibrutinib, by targeting NF-κB signaling and the UPR.