Daisuke Ando

This study uses long-read multi-omics sequencing to analyze DNA-to-RNA remodeling in recurrent astrocytoma, identifying patient-specific genetic and epigenetic changes and their impact on RNA isoforms and protein fate.

This study identifies ALKBH1 as a driver of codon-biased translation and tumor microenvironment remodeling in glioma, promoting stemness and immune evasion.

This study identifies staged translational remodeling in mouse cortex after ischemic stroke, showing changes in codon usage, ribosome occupancy, and frame-disruption events not captured by transcriptomics.

The paper analyzes tDRs across seven mouse tissues, identifying tissue-specific enrichment, diversity, and structural features of tDRs.

The paper shows that tRNA modifications regulate the translational response to mitochondrial stress by altering codon decoding and pathway activity.

The paper shows that tRNA modifications influence tissue-specific mRNA translation and codon optimization by analyzing tRNA and mRNA data from seven mouse tissues.