Author

Abdulrahman Mousa

Tohoku UniversityORCID 0009-0004-2740-0183Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 5 Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Organism:human· 4 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2

Frequent Co-Authors

Kuniyasu NiizumaiD· 5 shared Sherif RashadiD· 5 shared Daisuke AndoiD· 3 shared Shadi Al-MesitefiD· 3 shared Hidenori EndoiD· 2 shared Peter C. DedoniD· 2 shared Thomas J. BegleyiD· 2 shared Yuko IwasakiiD· 2 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersMolecular Biology

Kuniyasu NiizumaORCID

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5 papers

Recent·Most cited

ALKBH1 drives codon-biased, pro-oncogenic translation and tumor microenvironment remodeling in glioma via tRNA wobble oxidation

Atsushi Nakayashiki, Arata Nagai, Yuko Iwasaki, Abdulrahman Mousa, Moe Kumai, Munehiro Kimura, Shadi Al-Mesitef, Hiroshi Kanno, Shota Yamashita, Daisuke Ando, Yoshiteru Shimoda, Masayuki Kanamori, Keisuke Goda, Hidenori Endo, Sherif Rashad, Kuniyasu Niizuma

This study identifies ALKBH1 as a driver of codon-biased translation and tumor microenvironment remodeling in glioma, promoting stemness and immune evasion.

bioRxiv · Nov 28, 2025 · PreprintCancer Biology

Ischemic stroke induces staged translational remodeling in mouse cortex independent from transcriptional responses.

Sherif Rashad, Yuki Kitamura, Tomohito Nagai, Daisuke Ando, Abdulrahman Mousa, Hajime Ikenouchi, Hidenori Endo, Kuniyasu Niizuma

This study identifies staged translational remodeling in mouse cortex after ischemic stroke, showing changes in codon usage, ribosome occupancy, and frame-disruption events not captured by transcriptomics.

bioRxiv · Aug 15, 2025 · PreprintMolecular Biology

Transcriptome-Wide Analysis of HuR Function Identifies TXNIP-Mediated Redox Dysregulation in Osteocytes

Ziqiu Fan, Aseel Marahleh, Hideki Kitaura, Jiayi Ren, Abdulrahman Mousa, Fumitoshi Ohori, Kuniyasu Niizuma, Sherif Rashad, Hiroyasu Kanetaka

This study identifies HuR as a key regulator of osteocyte survival and metabolic adaptation under high glucose stress through transcriptome-wide analysis of its function.

bioRxiv · Aug 8, 2025 · PreprintMolecular Biology

Translational response to mitochondrial stresses is orchestrated by tRNA modifications.

Sherif Rashad, Shadi Al-Mesitef, Abdulrahman Mousa, Yuan Zhou, Daisuke Ando, Guangxin Sun, Tomoko Fukuuchi, Yuko Iwasaki, Jingdong Xiang, Shane R. Byrne, Jingjing Sun, Masamitsu Maekawa, Daisuke Saigusa, Thomas J. Begley, Peter C. Dedon, Kuniyasu Niizuma

The paper shows that tRNA modifications regulate the translational response to mitochondrial stress by altering codon decoding and pathway activity.

bioRxiv · Feb 14, 2024 · PreprintMolecular Biology

Angiogenin regulates mitochondrial stress and function via tRNA-derived fragments generation and impacting tRNA modifications.

Shadi Al-Mesitef, Keita Tominaga, Abdulrahman Mousa, Thomas J. Begley, Peter C. Dedon, Sherif Rashad, Kuniyasu Niizuma

This study shows that Angiogenin regulates mitochondrial stress and function by generating tRNA-derived fragments and altering tRNA modifications.

bioRxiv · Feb 13, 2024 · PreprintMolecular Biology