Author
Frederick National Laboratory for Cancer ResearchORCID 0009-0000-8325-0088Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Jessica L. Scales, Jayne A. Barbour, Alisa M. Goldstein…·Xiaohong R Yang
The paper identifies non-coding variants in CDKN2B that disrupt CTCF binding, reduce CDKN2A expression, and increase melanoma risk in families.
Aidan O’Brien, Hyunkyung Kong, Harsh Patel…·Laufey Thora Amundadottir
The paper identifies functional variants and VNTRs at the 5p15.33 locus using fine-mapping, MPRA, and CRISPRi screens, revealing their role in cancer susceptibility through antagonistic pleiotropy.
Supuni Thalalla Gamage, Roxane Khoogar, Shereen A. Howpay Manage…·Jordan L. Meier
This study shows that tRNA acetylation regulates stress signaling in mammals by affecting ribosome function and interacting with the Gcn2 kinase.
Katelyn E. Connelly, Katherine Hullin, Ehssan Abdolalizadeh…·Laufey Thora Amundadottir
The paper fine-maps a PDAC GWAS signal at chr1p36.33 and identifies KLHL17 as a target gene regulated by JunB/D, with potential implications for inflammation and PDAC risk.
Xiuxiu Lu, Venkata R. Sabbasani, Vasty Osei Amponsa…·Kylie J. Walters
The paper identifies a chemical scaffold targeting hRpn13, revealing a DEUBAD-lacking isoform upregulated in multiple myeloma and demonstrating its potential as a therapeutic target.