Mireia Osuna Lopez

This study maps tRNA expression dynamics across human hematopoiesis using sc-STM-seq and identifies tRNAs linked to stemness, differentiation, and cell lineages.

This paper introduces scPT-seq, a method to detect CRISPR mutations and transcriptional responses at single-cell resolution in vivo, revealing clonal markers and lineage dynamics in Drosophila intestine.

The paper identifies a centromeric satellite repeat in songbirds and shows it is absent from the germline-restricted chromosome (GRC), suggesting sequence changes underlie its programmed elimination.

The paper shows that glycolytic activity regulates germ layer proportions by modulating Nodal and Wnt signalling in mouse gastrulation.

The paper presents genome assemblies for three Platynereis species to support comparative genomic studies and explore their biology.

The paper evaluates genotype imputation in F2 crosses of inbred medaka lines, finding that imputation performance plateaus with increased sequencing coverage and develops a computational pipeline for cost-benefit analysis.